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Cataract

Research

Collage of images on the subject of cataract research

Instruments and methods

For nearly 40 years, we have been involved in major developments in cataract and lens surgery. Since 2008 we cooperate with VR Vision Research GmbH in our house in many development topics.

Here are some examples from the past:

Surgical instrumentation/ procedure

  • Cannula for capsular polishing, Pat. Application 1989

    Cannula for capsule polishing

  • Ultrasonic polishing of the lens capsule, registration 1999
  • Holding tweezers for ICL cartridges (Cartridge Holder, Katana, USA)
  • Implantation spatula tweezers (Deutschmann, Zittau)

    Implantationspinzette

  • Head positioning system for eye surgery, Pat. 1988
  • Irrigation hook with iris retractor, "Irrigation hook" (Geuder, Heidelberg)
  • Installation cannula for Vision Blue with Cat. mat. (Bausch& Lomb, Germany)

    Installationskanüle für Vision Blue

  • TCI Topography Controlled Incision, 2002
  • "TDI - a new concept in refractive cataract surgery", Array-roundtable, AMO, Kiel, 5.7.2003
  • TDI - Topography double incision, Poster, Lecture
  • WORCS (Wavefront Oriented Refractive Surgery), 2001, 2002
  • "Managing Astigmatism in Cataract Surgery: MICS, TDI, toric IOL or LASICAT?", Afro-Asian Congress of Ophthalmology, Istanbul, 18.-22.6.2004

    Removal of the eye lens

    • Crushing of the eye lens by means of optical energy, "laser phaco", with a patent application 1985
    • 2002 concept "Femtokatarakt", with a patent application 2003
    • 2004 Presentation of the concept (LASICAT, Video ASCRS 2004 in San Diego) 
    • "Limiting aspects in LASICAT", Poster WOC AbuDhabi 2012

    LASICAT - Femto laser-assisted cataract surgery

    The use of the femtosecond laser for cataract surgery, which we co-initiated in 2003/2004, is now used worldwide.

    Surgical instrumentation/ procedure

    • Cannula for capsular polishing, Pat. Application 1989

      Cannula for capsule polishing

    • Ultrasonic polishing of the lens capsule, registration 1999
    • Holding tweezers for ICL cartridges (Cartridge Holder, Katana, USA)
    • Implantation spatula tweezers (Deutschmann, Zittau)

      Implantation forceps

    • Head positioning system for eye surgery, Pat. 1988
    • Irrigation hook with iris retractor, "Irrigation hook" (Geuder, Heidelberg)
    • Installation cannula for Vision Blue with Cat. mat. (Bausch& Lomb, Germany)

      Installation cannula for Vision Blue

    • TCI Topography Controlled Incision, 2002
    • "TDI - a new concept in refractive cataract surgery", Array-roundtable, AMO, Kiel, 5.7.2003
    • TDI - Topography double incision, Poster, Lecture
    • WORCS (Wavefront Oriented Refractive Surgery), 2001, 2002
    • "Managing Astigmatism in Cataract Surgery: MICS, TDI, toric IOL or LASICAT?", Afro-Asian Congress of Ophthalmology, Istanbul, 18.-22.6.2004

    Removal of the eye lens

    • Crushing of the eye lens by means of optical energy, "laser phaco", with a patent application 1985
    • 2002 concept "Femtokatarakt", with a patent application 2003
    • 2004 Presentation of the concept (LASICAT, Video ASCRS 2004 in San Diego)
    • "Limiting aspects in LASICAT", Poster WOC AbuDhabi 2012

    LASICAT - Femto laser-assisted cataract surgery

    The use of the femtosecond laser for cataract surgery, which we co-initiated in 2003/2004, is now used worldwide (mehr bei KATARAKT --> Behand­lungs­mög­lich­keiten -->  2. LASICAT).

    Implants - IOL

    From 1984 to 1990 work was done on building up an IOL production for GDR needs. Shortly before completion of the project, it was canceled due to the new economic situation.

    Development of a new IOL design:

    The “Turtle IOL,” patent applications 1996, 2000 (for correction of individual aberration), 2006.

    Instead of two-point fixation, we designed a four-zone support system (disclosure document DE 196 37 693 A1, 1996).

    This basic strategy gave rise to three new basic variants:

    • Four open springy “feet”
    • Four closed haptics, also with three “ears”
    • Four-cornered plate haptics or with stiffer hinges

    Following this approach, numerous modifi­ca­tions were deve­loped in the following years. The centering of the intraocular lenses improved. There was less wrinkling of the capsules and less tilting. Thanks to the flexible haptics in diameter (fig.) in our “Turtle” concept, the new lens was able to adapt to capsules of different sizes and also be implanted in front of the capsule in the sulcus.

    Open flexible haptics

    ▲ Open flexible haptics

    Closed spring-loaded haptics

    ▲ Left & center: closed haptics/springy, right: plate haptics

    This resulted in various design variants (selection):

    The IOL developed by Oculentis is available in various designs.

    Other proprietary IOL concepts should also be mentioned, such as intraocular lenses

    • with pinhole apertures (GM 20 2013 104 393.1)
    • aberration-correcting (DE 100 25 320 A1, 2000), (DE 10 2009 006 023 A1, 2009)
    • individual color filters (DE 10 2006 018 913 A1).

    Capsular tension rings

    Capsular tension rings with Coloboma aperture

    In addition to a total lack of iris aperture function, even minor defects can lead to imaging errors and glare. These include congenital colobomas or those resulting from accidents. For these indications, we worked with Mr. Morcher to design a whole series of rings with segmented apertures. These were then implanted for a wide variety of indications, and the results were presented in the USA at the ASCRS 1998.

    Capsule tension ring for a normal eye  Capsule tension ring for a myopic eye  Capsule tension ring for a myopic eye  

    For the congress video on implantation in albinism, we received both one of the coveted Oscars at the ASCRS film festival and the poster prize in recognition of the overall capsule tension ring concept.

    Dr. Rasch receives the Academy Award for Best Picture  Film Oscar from 1998

    ▲ Dr. Rasch receives the Academy Award for Best Picture

    The ASCRS video library recognized the concept as an important innovation and Dr. Rasch as the “innovator.” The capsule tension rings with iris and coloboma apertures are now manufactured by several companies and implanted worldwide. The Dutch company Ophtec produced colored versions in brown and green.

    General information

    Capsule tension rings are additional implants for lens surgery. They are inserted into the capsular bag together with the artificial lenses in order to “tension” it. This can be useful for better centering of the IOL or in cases of loose fibers in the lens suspension.

    Originally, capsular tension rings had small circular loops at both ends of the rings, which occasionally led to perforation of the capsular bag if it was very loose.

    Original capsule tension ring

    ▲ Original capsule tension ring

    The idea arose to give the leading end of the clamping rings a larger curve. This significantly reduced the risk of capsule bag perforation (publication DE 196 37 692 A1, 1996). Here, too, the first model was manufactured for us by Morcher (Type 2). We would like to take this opportunity to express our sincere thanks to Mr. Morcher's team in Stuttgart for their constructive cooperation over many years.

    Numerous companies adopted this design. Today, it is the global standard.

    Illustration of a new capsule tension ringIllustration of a new capsule tension ring

    ▲ left: Fig. from disclosure document “The new guide end,” right: Modification with “sharp edge”

    A completely different problem can arise when implanting toric IOLs (for more severe corneal curvature). In rare cases, the capsular bag is not round and the lens that has already been implanted may twist slightly out of the desired position. For such cases, we designed a capsule tension ring that prevents unwanted rotation of the IOL: the Type 50 B as a “rotation brake.”

    Capsule tension ring as a rotation brake

    ▲ Capsule tension ring as a rotation brake, Fa Morcher, Typ 50B

    Capsule tension rings with iris diaphragms

    The iris of the eye acts as a diaphragm with the pupil for sharper vision, similar to the “iris diaphragm” of classic cameras. If the iris is missing or has major defects (due to accident, illness, or congenital causes), there is no sharp image on the retina. Patients are usually severely dazzled, for example, in cases of albinism.

    Iris defects  panel cover

    ▲ Left: Iris defects, right: Plate aperture

    The pupil-forming implants available on the market in the 1990s consisted mainly of black PMMA plates with a hole that filled the front of the eye. These relatively large implants often led to complications in the cornea and increased pressure. When a patient with such iris defects was scheduled for lens replacement surgery (cataract surgery), we came up with the idea of implanting an aperture at the same time as the artificial lens during the procedure: in the capsular bag.

    The advantages of the new concept:

    • smaller incision,
    • smaller implant,
    • relaxation of the lens capsule,
    • no disadvantages for neighboring tissue, fewer complications.

    Within a short period of time, the Morcher company in Stuttgart produced several models of capsule tension rings with ring-shaped aperture functions.

    When the implants were ready, we lacked the first “suitable patient.” Then a request came in from New York: Dr. Ken Rosenthal had a difficult case for which he thought the aperture ring he had heard about would be suitable. So it came about that we performed the first operation with this novel implant there in the USA. He operated, Dr. Rasch was to assist him and tell him how to implant the capsular tension rings. After the successful operation, he asked with a smile: “It was your first case too?”

    Dr. Rosenthal receives the Academy Award for Best Picture  Dr. Rasch and Dr. Rosenthal

    ▲ Dr. Rosenthal at the American Congress of Eye Surgery and the Academy Awards ceremony

    The following year, Dr. Rosenthal received a film Oscar from the ASCRS, the American Society of Cataract and Refractive Surgery. Further awards followed ...

    In addition to TV reports accompanying patients, ARD also reported on our work in the Potsdam eye surgery center and on the “artificial iris” from Potsdam in its Tagesthemen news program.

    Outlook - The future has begun

    LAL - Light Adjustable Lense

    The LAL is an intraocular lens that can be modified in terms of its refractive power after implantation in the eye using special UV radiation. This makes it possible to achieve the goal of “vision without glasses” even more accurately. In 2008, the Potsdam Eye Clinic in the Graefe House was one of the first clinics in Europe to introduce this new technology. With the development of special additional implants (disclosure document DE 10 2010 017 240 A1), we contributed to improving the procedure and increasing safety for our patients.

    We designed sector apertures for the capsular bag as radiation protection for “light adjustable lenses” and patients with albinism.

    Use of an aperture on the patient  Use of an aperture on the patient  Use of an aperture on the patient  

    ▲ Use of an aperture on the patient

    The second generation of LAL is now set to open up new perspectives for cataract surgery.

    General information

    Capsule tension rings are additional implants for lens surgery. They are inserted into the capsular bag together with the artificial lenses in order to “tension” it. This can be useful for better centering of the IOL or in cases of loose fibers in the lens suspension.

    Originally, capsular tension rings had small circular loops at both ends of the rings, which occasionally led to per­fo­ration of the capsular bag if it was very loose.

    Original capsule tension ring

    ▲ Original capsule tension ring

    The idea arose to give the leading end of the clamping rings a larger curve. This signi­fi­cant­ly reduced the risk of capsule bag perforation (publication DE 196 37 692 A1, 1996). Here, too, the first model was manu­fac­tured for us by Morcher (Type 2). We would like to take this opportunity to express our sincere thanks to Mr. Morcher's team in Stutt­gart for their constructive cooperation over many years.

    Numerous companies adopted this design. Today, it is the global standard.

    Capsule tension ring
    Capsule tension ring

    ▲ left: Fig. from disclosure document “The new guide end,” right: Modification with “sharp edge”

    A completely different problem can arise when implanting toric IOLs (for more severe corneal curvature). In rare cases, the cap­su­lar bag is not round and the lens that has already been implanted may twist slight­ly out of the desired position. For such cases, we designed a capsule tension ring that prevents unwanted rotation of the IOL: the Type 50 B as a “rotation brake.”

    Capsule tension ring as a rotation brake

    ▲ Capsule tension ring as a rotation brake, Fa Morcher, Typ 50B

    Capsule tension rings with iris diaphragms

    The iris of the eye acts as a diaphragm with the pupil for sharper vision, similar to the “iris diaphragm” of classic came­ras. If the iris is missing or has major defects (due to acci­dent, illness, or congenital causes), there is no sharp image on the retina. Patients are usually severely blinded, for example in cases of albinism.

    Iris defects  panel cover

    ▲ Left: Iris defects, right: Plate aperture

    The pupil-forming implants available on the market in the 1990s mostly con­sis­ted of black PMMA plates with a hole that filled the front of the eye. These relatively large implants often led to complications in the cornea and increased pressure. When a patient with such iris defects was scheduled for lens replacement surgery (cataract surgery), we came up with the idea of implanting an aperture at the same time as the artificial lens during the procedure: in the capsular bag.

    The advantages of the new concept:

    • smaller incision,
    • smaller implant,
    • relaxation of the lens capsule,
    • no disadvantages for neighboring tissue, fewer complications.

    Within a short period of time, the Morcher company in Stuttgart pro­duced several models of capsule ten­sion rings with ring-shaped aperture functions.

    When the implants were ready, we lacked the first “suitable patient.” Then a request came in from New York: Dr. Ken Rosenthal had a difficult case for which he thought the aperture ring he had heard about would be suitable. So it came about that we performed the first operation with this novel implant there in the USA. He operated, Dr. Rasch was to assist him and tell him how to implant the capsular tension rings. After the successful operation, he asked with a smile: “It was your first case too?”

    Dr. Rosenthal receives the Academy Award for Best Picture
    Dr. Rasch and Dr. Rosenthal

    ▲ Dr. Rosenthal at the American Congress of Eye Surgery and the Academy Awards ceremony

    The following year, Dr. Rosenthal received a film Oscar from the ASCRS, the American Society of Cataract and Refractive Surgery. Further awards followed ...

    In addition to TV reports accompanying patients, ARD also reported on our work in the Potsdam eye surgery center and on the “artificial iris” from Potsdam in its Tages­themen news program.

    Capsule tension rings with coloboma covers

    In addition to a total lack of the iris's aperture function, even minor defects can lead to imaging errors and glare. These include congenital colobomas or those resulting from accidents. For these indications, we worked with Mr. Morcher to design a whole series of rings with segmented apertures. These were then implanted for a wide variety of indications, and the results were presented in the USA at the ASCRS 1998.

    Capsular tension ring Coloboma iris Normal eye
    Capsular tension ring with coloboma shutter for myopic eyes
    Capsular tension ring with coloboma shutter for myopic eyes

    For the congress video on implantation in albinism, we received both one of the coveted Oscars at the ASCRS film festival and the poster prize in recog­ni­tion of the overall capsule tension ring concept.

    Dr. Rasch receives the Academy Award for Best Picture  Film Oscar from 1998

    ▲ Dr. Rasch receives the Academy Award for Best Picture

    The ASCRS video library recognized the concept as an important innovation and Dr. Rasch as the “innovator.” The capsule tension rings with iris and colo­boma apertures are now manu­fac­tured by several companies and implanted worldwide. The Dutch company Ophtec produced colored versions in brown and green.

    Outlook - The future has begun

    LAL - Light Adjustable Lense

    The LAL is an intraocular lens that can be modified in terms of its refractive power after implantation in the eye using special UV radiation. This makes it possible to achieve the goal of “vision without glasses” even more accurately. In 2008, the Potsdam Eye Clinic in the Graefe House was one of the first clinics in Europe to introduce this new tech­no­lo­gy. With the development of special additional implants (disclosure document DE 10 2010 017 240 A1), we contributed to improving the proce­dure and increasing safety for our patients.

    We designed sector apertures for the capsular bag as radiation protection for “light adjustable lenses” and patients with albinism.

    Use of an aperture on the patient  Use of an aperture on the patient  Use of an aperture on the patient  

    ▲ Use of an aperture on the patient

    The second generation of LAL is now set to open up new perspectives for cataract surgery.

    Ring apertures

    For special questions, closed apertures can also be implanted in the capsular bag as an alter­native to the capsular tension rings with iris apertures. In the case of UV irradiation of LAL-IOL, the retina can thus be pro­tected against possible damage. These apertures were developed by us (VR Vision Research GmbH) together with the company Morcher/ Stuttgart and implanted in the eye clinic for the first time in 2015.

    For other indications (eg irreversible my­dria­sis, aniri­dia, albinism) or IOL, the inner diameter is smaller, 4mm.

    Basic research and concepts

    All our ideas, concepts and the resul­ting developments spring from the questions of everyday life. The goal is always to improve the diagnosis on the eye or the quality of our operations. With our contributions we help to improve eye surgery worldwide.

    LASICAT - Femtosecond laser-assisted cataract surgery

    Multi-functional diagnostics

    In the 1970s and 1980s, diagnostic devices in ophthalmology consisted primarily of precision mechanical and optical components. In Western Europe, the first devices came onto the market in which computer-assisted measurement techniques played an increasingly important role.

    Overview of various individual eye examinations

    View of a setup for multiple tests on a device<

    However, they all had one thing in common:

    A separate device with a single function was developed for each measurement task.

    This often meant that patients had to move from one examination chair to another. So-called examination units represented the first step forward. Here, the individual devices were swung in front of the patient one after the other.

    At the end of the 1970s, Dr. Rasch had the good fortune—as was usually the case by chance—to meet one of the leading minds in the GDR in the field of optoelectronics, Prof. Jürgen Waldmann. Numerous ideas, concepts, and patent applications for a new type of eye diagnostics were developed jointly in the following years. Interestingly, they even developed ideas for novel solutions for optoelectronics together: one example is a novel chip, not yet realized at the time, that combines emitters and sensors, i.e., illumination and receivers, on a single chip. (Patent specification DD 233 463 A1, 1984) It was not until much later that this new generation of chips became a reality.

    Prof. Jürgen Waldmann

    ▲ Prof. Jürgen Waldmann

    At some point, the idea arose of combining a range of very different eye examinations in a single device using specially designed arrangements of optics, optoelectronic (and other) sensors, and emitters (e.g., LEDs): “Multifunctional diagnostics for the eye.” (Patent specification DD 233 299 A1, 1984)

    A direct coupling of illumination, diagnostics, and radiation therapy in a single element also dates from this period (PS DD 250 590 A1, 1985). Companies specifically approached in Germany rejected the idea with disbelief. Even the opportunity to demonstrate a simple prototype at various international trade fairs generated a lot of interest but no potential buyers.

    Today, this “way of thinking” can be found in most ophthalmic diagnostic devices. It has also become common practice to think multifunctionally in other areas (see smartphones).

    Collage from the first model of a multifunctional camera to the modern Cassini measuring device

    Image 1: First model, 1988; Images 2-4: Projection of light points onto the cornea to determine the corneal topography (image taken with the first CCD matrix camera, made in the GDR) “Multifunctional camera” – first functional model in 1988, Image 5: Topography 30 years later: Cassini-2018 (from left to right)

    Another example from basic research

    Can visual acuity be improved “endlessly” with personalized LASIK?
    With the development of diagnostic devices for measuring aberrations in the eye, refractive surgery has also created a way to surgically correct these aberrations and thus increase visual acuity. There have been euphoric reports in the media about the new surgical possibilities: 400% visual acuity?

    Since this could not be the case and current visual acuity always depends on many factors, we examined over 2,000 eyes of young people in Potsdam to demonstrate the dependence of aberrations on a wide variety of influencing factors. The poster presented at the European Society of Cataract and Refractive Surgeons (ESCRS) Congress in 2001 became the first critical contribution to personalized laser surgery internationally and was honored with the (only) award at the congress at that time.

    Cover of FOCUS magazine on the topic of “Everything in focus without glasses”  Dr. Rasch at the European Congress for Refractive Surgery 2001

    ▲ Left: FOCUS magazine; right image: Poster award from the European Society of Cataract and Refractive Surgeons (ESCRS) (2001)

    Iris registration for refractive surgery

    Can the axis of corneal curvature measured in a sitting position be safely transferred to patients who are treated in a lying position?

    In the surgical correction of refractive errors, the correction of corneal curvature (astigmatism) is an essential part of the treatment. We wondered how the axis position changes from sitting during measurement to lying down during surgery. In a study conducted in 1999, we were able to show that an eye can rotate by 10 degrees or more when the body position changes. This can lead to significant deviations from the desired surgical result. Our resulting demand on the industry to develop a technical solution that would allow the axis position to be transferred and corrected from a sitting to a lying position using iris recognition was rejected or ignored at the time.

    Today, all lasers for personalized treatments have such capabilities, both for laser correction of the cornea (LASIK) and for femtosecond laser-assisted cataract surgery (LASICAT). This demand of ours at the Potsdam Eye Clinic in the Graefe House has been implemented.

    Aberrometry at iDesign with iris registration  Eye recognition on the VISX  

    ▲ Left: Aberrometry on iDesign with iris registration, right: Eye recognition on VISX

    After measuring the eye with the Cassini Topographer: Recognizing the iris structure with LensAR  Treatment planning at LensAR  

    ▲ Left: After measuring the eye with the Cassini Topographer: recognizing the iris structure on the LensAR; right: treatment planning on the LensAR

    Varia

    • "Do we need the CIA in Cataract Surgery? Endoscopic follow-up during cataract surgery: Initial admission January 13, 1999 Potsdam, published in Videocompetition of ASCRS Seattle 1999, Videocompetition of DOC Nuremberg 1999
    • "Do we need the CIA in Cataract Surgery?", Videocompetition, XVlI.Congress ESCRS, Vienna 1999, 2nd prize, Art.Cat.
    • "Interface cleaning by I/A-Tunnel-Technique – case report
    • "Topographie oriented Double-Incision (TDI) – a new concept in refractive Cataract surgery", ESCRS Munich, 06.-10.09.2003
    • "Topography-Oriented Double Incision – A new concept for Managment of Astigmatism in Refractive Cataract Surgery", ASCRS, San Diego, 01.-05.05.2004
    • "Laser in Cataract Surgery – LASICAT", Afro-Asian Congress of Ophthalmology, Istanbul, 18.-22.06.2004
    • "Topography oriented Double-Incision (TDI) – a new concept for management astigmatism in refractive Cataract surgery", Afro-Asian Congress of Ophthalmology, Istanbul, 18.-22.06.2004
    • "Topographie oriented Double-Incision (TDI) – a new concept in refractive Cataract surgery", ESCRS Paris, 18.-22.09.2004
    • "Laser in Cataract Surgery - LASICAT", ESCRS Paris, 18.-22.09.2004
    • "Management and implantation of the Acriflex 62 Toric IOL", ASCRS, San Francisco, 17.-22.03.2006
    • "Management and implantation of the ACRFLEX 62 VR TI—the first personalized and individually produced toric IOL. Initial results.", DOG, Nürnberg, 25.-28.05.2006
    • "Management and Implantation of LU 804 VR-T (Toric Individual) the first individual produced toric IOL." XII. Oph. Balticum, Riga, 24.-26.08.2007
    • Collaboration on basic research and development of wavefront-guided diagnostics and development of new surgical laser technologies Volker Rasch, Axel Weber
    • "Reproducibility and Reliability of the Wavefront Analysis by Zywave Aberrometer - Influences of Zywave, by Patients and Examiners", Posterpräsentation, 5th ESCRS Winter Refractive Surgery Meeting, Cannes 2001, prize of congress

    LASICAT - femtolaser-assisted cataract surgery

    Multi-functional diagnostics

    In the 1970s and 1980s, diagnostic devices in ophthalmology consisted primarily of pre­ci­sion mechanical and optical components. In Western Europe, the first devices came onto the market in which computer-assisted measure­ment techniques played an increa­singly important role.

    Overview of various individual eye examinations

    View of a setup for multiple tests on a device

    However, they all had one thing in common:

    A separate device with a single function was developed for each measurement task.

    This often meant that patients had to move from one examination chair to another. So-called examination units represented the first step forward. Here, the individual devices were swung in front of the patient one after the other.

    At the end of the 1970s, Dr. Rasch had the good fortune—as was usually the case by chance—to meet one of the leading minds in the GDR in the field of optoelectronics, Prof. Jürgen Wald­mann. Numerous ideas, concepts, and patent applications for a new type of eye diagnostics were developed jointly in the following years. Interestingly, they even developed ideas for novel solutions for optoelectronics together: one example is a novel chip, not yet realized at the time, that combines emitters and sensors, i.e., illumination and receivers, on a single chip. (Patent specification DD 233 463 A1, 1984) It was not until much later that this new generation of chips became a reality.

    Prof. Jürgen Waldmann

    ▲ Prof. Jürgen Waldmann

    At some point, the idea arose of com­bining a range of very different eye examinations in a single device using specially designed arrangements of optics, optoelectronic (and other) sensors, and emitters (e.g., LEDs): “Multifunctional diagnostics for the eye.” (Patent specification DD 233 299 A1, 1984)

    A direct coupling of illumination, dia­gnos­tics, and radiation therapy in a single element also dates from this period (PS DD 250 590 A1, 1985). Com­panies specifically approa­ched in Ger­many rejected the idea with dis­be­lief. Even the opportunity to demon­strate a simple prototype at various inter­national trade fairs generated a lot of interest but no potential buyers.

    Today, this “way of thinking” can be found in most ophthalmic diagnostic devices. It has also become common practice to think multifunctionally in other areas (see smart­phones).

    CCD matrix camera

    Image 1: First model, 1988; Images 2-4: Projection of light points onto the cornea to determine the corneal topography (image taken with the first CCD matrix camera, made in the GDR) “Multifunctional camera” – first functional model in 1988, Image 5: Topography 30 years later: Cassini-2018 (from left to right)

    Another example from basic research

    Can visual acuity be improved “endlessly” with personalized LASIK?
    With the development of diagnostic devices for measuring aber­rations in the eye, refractive surgery has also created a way to surgically correct these aber­rations and thus increase visual acuity. There have been euphoric reports in the media about the new surgical possibilities: 400% visual acuity?

    Since this could not be the case and current visual acuity always depends on many factors, we examined over 2,000 eyes of young people in Potsdam to demonstrate the dependence of aber­rations on a wide variety of influencing factors. The poster presented at the European Society of Cataract and Re­frac­tive Surgeons (ESCRS) Congress in 2001 became the first critical con­tri­bu­tion to personalized laser surgery inter­nationally and was honored with the (only) award at the congress at that time.

    Cover of FOCUS magazine on the topic of “Everything in focus without glasses”  Dr. Rasch at the European Congress for Refractive Surgery 2001

    ▲ Left: FOCUS magazine; right image: Poster award from the European Society of Cataract and Refractive Surgeons (ESCRS) (2001)

    Iris registration for refractive surgery

    Can the axis of corneal curvature measured in a sitting position be safely transferred to patients who are treated in a lying position?

    In the surgical correction of refractive errors, the correction of corneal cur­vature (astig­ma­tism) is an essential part of the treatment. We wondered how the axis position changes from sitting during measure­ment to lying down during surgery. In a study conducted in 1999, we were able to show that an eye can rotate by 10 degrees or more when the body position changes. This can lead to significant deviations from the desired surgical result. Our resulting demand on the industry to develop a technical solution that would allow the axis position to be transferred and correc­ted from a sitting to a lying position using iris recognition was rejected or ignored at the time.

    Today, all lasers for personalized treatments have such capabilities, both for laser correc­tion of the cornea (LASIK) and for femto­second laser-assisted cataract surgery (LASICAT). This demand of ours at the Potsdam Eye Clinic in the Graefe House has been implemented.

    Aberrometry at iDesign with iris registration  Eye recognition on the VISX  

    ▲ Left: Aberrometry on iDesign with iris registration, right: Eye recognition on VISX

    After measuring the eye with the Cassini Topographer: Recognizing the iris structure with LensAR  Treatment planning at LensAR  

    ▲ Left: After measuring the eye with the Cassini Topographer: recognizing the iris structure on the LensAR; right: treatment planning on the LensAR

    Varia

    • "Do we need the CIA in Cataract Surgery? Endoscopic follow-up during cataract surgery: Initial admission January 13, 1999 Potsdam, published in Videocompetition of ASCRS Seattle 1999, Videocompetition of DOC Nuremberg 1999
    • "Do we need the CIA in Cataract Surgery?", Videocompetition, XVlI.Congress ESCRS, Vienna 1999, 2nd prize, Art.Cat.
    • "Interface cleaning by I/A-Tunnel-Technique – case report
    • "Topographie oriented Double-Incision (TDI) – a new concept in refractive Cataract surgery", ESCRS Munich, 06.-10.09.2003
    • "Topography-Oriented Double Incision – A new concept for Managment of Astigmatism in Refractive Cataract Surgery", ASCRS, San Diego, 01.-05.05.2004
    • "Laser in Cataract Surgery – LASICAT", Afro-Asian Congress of Ophthalmology, Istanbul, 18.-22.06.2004
    • "Topography oriented Double-Incision (TDI) – a new concept for management astigmatism in refractive Cataract surgery", Afro-Asian Congress of Ophthalmology, Istanbul, 18.-22.06.2004
    • "Topographie oriented Double-Incision (TDI) – a new concept in refractive Cataract surgery", ESCRS Paris, 18.-22.09.2004
    • "Laser in Cataract Surgery - LASICAT", ESCRS Paris, 18.-22.09.2004
    • "Management and implantation of the Acriflex 62 Toric IOL", ASCRS, San Francisco, 17.-22.03.2006
    • "Management and implantation of the ACRFLEX 62 VR TI—the first personalized and individually produced toric IOL. Initial results.", DOG, Nürnberg, 25.-28.05.2006
    • "Management and Implantation of LU 804 VR-T (Toric Individual) the first individual produced toric IOL." XII. Oph. Balticum, Riga, 24.-26.08.2007
    • Collaboration on basic research and development of wavefront-guided diagnostics and development of new surgical laser technologies Volker Rasch, Axel Weber
    • "Reproducibility and Reliability of the Wavefront Analysis by Zywave Aberrometer - Influences of Zywave, by Patients and Examiners", Posterpräsentation, 5th ESCRS Winter Refractive Surgery Meeting, Cannes 2001, prize of congress

    Do you need more information or
    would you like advice?

    The team at the Potsdam Eye Clinic and Practice Dr. Rasch will be happy to advise you.

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